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Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1

The Bright Set contains three targeted formulations that contain well-studied brightening ingredients to help visibly target uneven skin tone, while brightening dull skin

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PQQ triggers the creation of new mitochondria (mitochondrial biogenesis via PGC-1alpha)

The work of Raun et al., 1998 and Svensson et al., 2000 provides the fundamental characterisation, while Kojima and Kangawa, 2005 supply the physiological context of the ghrelin system