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Symptoms of folate deficiency include poor growth, tongue inflammation, gingivitis, loss of appetite, shortness of breath, diarrhoea, irritability, forgetfulness, and mental sluggishness

Patients who already have exceptionally high pyridoxine levels or signs of pyridoxine toxicity (such as sensory neuropathy) should not continue to receive high-dose supplementation until those symptoms resolve

People under high stress or with digestive issues that impair nutrient absorption

Reframing the question from "Does B12 affect kidney function?" to " Does B12 affect kidney function in my specific situation?" is essential

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