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Continuous translocation of bacteria and its products stimulate the immune cells after identification by pathogen-recognition receptors, typically TLRs, causing overwhelming inflammatory response via producing inflammatory cytokines (25)

Biodegradation 29 (6), 525541

For the species-level analysis of Bifidobacterium , taxonomic assignments were conducted by aligning each 16S rRNA V3-V4 sequence to the RefSeq database of 16S rRNA gene sequences released by NCBI ( updated at 2023.4.15) using the qiime feature-classifier classify-consensus-blast command with the parameter --p-perc-identity 0.99