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Reduced expression of AST, ALT, and ALP was positively correlated with the diminished release of cytochrome c that consequently inhibit the BAX and caspase 3-mediated apoptotic signaling (Figures 5, 6)

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Loss of appetite and weight loss: A reduced appetite can be a telltale sign, potentially leading to weight loss

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In a systematic review and meta-analysis on the safety and efficacy of DOACs and warfarin in elderly patients with atrial fibrillation, researchers concluded that there were no significant differences in the DOACs studied (rivaroxaban, dabigatran, apixaban, and edoxaban) in terms of stroke or blood clot prevention