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111 CCL1, the main ligand for CCR8, not only induces Treg migration but also promotes Treg differentiation and the expression of effector molecules such as CD39, IL-10, and granzymes

Pale flat areas without mucosal folds were measured and are expressed as the percentage of the entire area of the blood-deprived colon segment (mean SD)

Tumor colonization Tumor cells undergo clonal selection under microenvironmental pressures, acquiring EMT phenotypes and cancer stemness propertiesdual hallmarks of metastatic competence [178, 179]