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Growth enhancement of transgenic mice expressing human insulin-like growth factor-I

Studies have revealed that the GH/IGF-1 axis plays a key role in the aging process of humans and animals ( GH receptor is a member of the class I cytokine receptor family and exists in almost all cell types in the human body (Waters et al., 1999)

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Conversely, proline and GPOX accumulation were higher in the sensitive variety compared to the tolerant variety

In clinical practice, RA is typically managed through pharmacologic therapy, surgical treatment, and non-pharmacologic interventions