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Implications of oxidative stress in the pathogenesis and treatment of hyperpigmentation disorders

10.1152/ajplung.00098.2012 4 Alajbegovic-HalimicJ.ZvizdicD.Alimanovic-HalilovicE.DodikI.DuvnjakS

Invest., 88, 396402

In metabolic disease contexts, studies have found that supraphysiological doses of coenzyme Q 10 (CoQ 10 ) can specifically upregulate SQOR expression and simultaneously inhibit key enzymes (CBS and CSE) in the transsulfuration pathway, thereby reshaping the serinefolate cycle and nucleotide metabolism (Gonzlez-Garca et al., 2020)