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For instance, during sleep, the UPS facilitates the clearance of neurotoxic proteins like -amyloid, and disruptions in circadian regulation can impair this clearance, contributing to disorders such as Alzheimers disease (Xie et al., 2013

[27] results were in consistence to our results

The spent or oxidised glutathione (GSSG), much like steam, then has to be cooled to reload the fire engine

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Acknowledgements: This research was supported by a grant from Ministry of Science, Education and Sports, Republic of Croatia and there is no existing personal conflicts of interest with any of the authors