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5 End-centered expression profiling using cap-analysis gene expression and next-generation sequencing

Another study using the chronic mild stress paradigm revealed that mice with decreased sucrose preference and increased immobility in the tail suspension test (i.e., learned helplessness) also showed damaged mitochondrial ultrastructure, impaired respiration rates, and altered membrane potentials in the hippocampus, hypothalamus, and the cortex (Gong et al., 2011)

Could it cause immunosuppression or metabolic toxicity

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Results: For patients treated for hematological malignancies, the most prominent IgG Fc glycosylation differences between donors and recipients pre-HSCT were observed in the galactosylation, which was lower in the patients as compared to the donors independently of the IgG subclass