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The third layer, lamina propria, is located under the epithelium and forms the enteric immune system that consists of a large number of leukocytes with macrophages and dendritic cells being the dominant cell types (Shemtov et al., 2023)

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It modulates the activity of inflammatory cytokines and helps maintain the balance between pro-inflammatory and anti-inflammatory signals

There was no demonstration that I could tell that it was a single pure isolated substance, Mapp said