overdose b12 injection Compounded Hydroxocobalamin (Vitamin B12) Vitamin B12: Overdose and Side

Contraindications include known hypersensitivity to any component of the injection (including cobalt hypersensitivity), a history of severe reactions to thiamine/pyridoxine/cobalamin injections, and Lebers hereditary optic neuropathy (for B12-containing products)

Oral supplements must first pass through the digestive tract, where a portion of the active compound can be degraded or poorly absorbed, especially if gastrointestinal issues are present

Its a story of immense promise that ultimately fell short of the specific, rigorous endpoints required for a commercial drug

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Cell Chemical Biology