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Fiorentini D, Cappadone C, Farruggia G, Prata C

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15 Mechanistic actions of TPE include removing toxic agents, cytokines, and abnormal inflammatory proteins 20 such as amyloid beta (A) proteins 21

Compared to mAChRs, nAChRs have a reduced affinity for the natural agonist ACh, which suggests that they may be involved in negative feedback mechanisms linked with growing levels of ACh