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In a diet-induced NASH rat model, administration of 1,25 VD3 was shown to reshape the hepatic cytokine milieu by suppressing pro-inflammatory mediators such as TNF- and IL-1, while simultaneously enhancing anti-inflammatory cytokines, including IL-10 and IL-4

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[email protected] References 1: Health Topics, Noncommunicable Diseases, Diabetes

Probiotics also affect the activity of various immune cells, including dendritic cells, macrophages, and T cells, enhancing the guts ability to respond appropriately to pathogens (109)