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2.3 Collection of clinical data and detection of biochemical indexes 2.3.1 General information collection A standardised electronic medical record system was utilised to document patients baseline information, encompassing age, gender, BMI, waist-to-hip ratio, and current medication history

Animals were kept on a 12:12 lightdark cycle and provided ad libitum access to water and compositionally balanced normal rat chow following protocols of the Animal Care and Use Committee, College of Pharmacy, King Saud University

Glutathione and Vitamin C have a powerful relationship

A search strategy will be developed using a combination of medical subheadings words and keywords include: Pre-diabetic State or Pre-diabetic States or state, Pre-diabetic or States, Pre-diabetic or Pre-diabetes and Probiotics or Probiotic or Synbiotics or Synbiotic or Pre-biotics or Pre-biotic. This review will be conducted according to the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement (32)

Nutr Diabetes 7, 304