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151 Single-cell RNA sequencing of ~50,000 transcriptomes from young (3 - 4 months) and old (2123 months) mice demonstrated substantial regional heterogeneity of age-dependent changes indicating that ageing of neurones and glia may develop through distinct molecular pathways

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PMID 16195333

Overall, Nrf2 and NF-B interact with each other to coordinate antioxidant and inflammatory responses