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People who are prone to sleeplessness develop chronic insomnia

GPER-1 has been found to be widely expressed in NSPCs (Zhang et al., 2019

Washington, DC, USA: 1984

These pathways include the ASK1 pathway, which initiates proapoptotic signaling through JNK and p38 pathways, leading to the phosphorylation of proapoptotic proteins like BAD, BIM, and BAX