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These findings reinforced ours, which illustrated that MSG elicited marked perturbation in the redox status, evidenced by the diminution in antioxidant defense machinery, SOD and TAC levels, in conjunction with the sharp rise in the production of ROS, demonstrated by the elevated level of lipid peroxidation marker, MDA, in comparison to the normal control group

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Phenytoin, phenobarbital, ephedrine, and rifampin may enhance the metabolic clearance of corticosteroids resulting in decreased blood levels and lessened physiologic activity, thus requiring adjustment in corticosteroid dosage