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This can serve as a therapeutic target against aging and age-related disorders.70 For example, rapamycin, an mTOR inhibitor restores autophagy and delays senescence-related diseases.71,72 Similarly, spermidine induces autophagy and improves cellular renewal, thus promoting longevity.73 Regulation of Oxidative Stress and DNA Damage Response: Oxidative stress and DNA damage are major drivers of senescence

MK-677 (ibutamoren) is a non-peptide GH secretagogue taken orally with reliable systemic activity

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Western blotting further confirmed that p-IRE1- levels were highest in the IFN- treated cells, followed by NAC, and IFN-+NAC treatments, with levels notably reduced in the Anta applied groups and the control

MOTS-c is described as a motion simulator that systematically regulates glucose metabolism in the body and the role of muscle insulin (15)