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that AFB1, as the parent compound, inhibited rat liver mitochondrial electron transport at the antimycin A-sensitive site (10) and postulated subsequently (5) that the enhanced liver cell necrosis and acute toxicity observed in the low-protein animals could be due to the low rate of metabolism and clearance of AFB1 with a consequent effect on mitochondrial respiration

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NPR1 Promotes Its Own and Target Gene Expression in Plant Defense by Recruiting CDK8

Chem Res Toxicol 24:549558 Starckx S, Batheja A, Verheyen GR, Jonghe SD, Steemans K, Dijck BV, Singer M, Bogdan N, Snoeys J, Vinken P, Sasaki JC, Gompel JV, Guzzie-Peck P, Lampo A, Lammens L (2013) Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats