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B., Edsmyr, F

PINK (PTEN-induced putative kinase1)/Parkin pathway is the most well-characterized signaling that orchestrates mitochondrial degradation in PD (Doxaki and Palikaras, 2020)

SouthwickSPaigeSMorganC3rdBremnerJKrystalJCharneyD

However, current evidence demonstrates limited clinical utility for available immunotherapeutics in GBM, due to a highly immunosuppressive TME and metabolic characteristics that impair anti-tumor immune response