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Weekly Dosing Schedule for the First Month After the first week, a weekly dosing schedule is used for the next month

In this case, despite markedly low vitamin B12 levels and deep sensory impairment, there were no findings of anemia, upper motor neuron signs (such as hyperreflexia or a positive Babinski sign), or abnormal signal intensities in the posterior columns of the cervical spinal cord on MRI [7]

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The effect of vitamin B12 and folic acid supplementation on serum homocysteine, anemia status and quality of life of patients with multiple sclerosis

If you have sub-optimal levels with symptoms, its worth a trial of B12 even if your serum B12 levels are normal