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2021 NEJM): 1961 patients, 14.9% weight loss at 68 weeks

Free Radic Biol Med 217, 6067.Google Scholar Halliwell, B, Tang, RMY & Cheah, IK

-hydroxybutyrate, the most abundant ketone body, is mainly synthesized in the liver from circulating fats during times of starvation, extended exercise, or when carbohydrate intake is limited [41]