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Recent studies suggest that intestinal I/R injury may alter this delicate equilibrium, facilitating the passage of peripheral inflammatory signals to the brain, leading to neuroinflammation, and eventually compromising cognitive performance (Song et al., 2020

elegans, was instrumental in unearthing the genetic underpinnings of apoptosis and revealing a predetermined fate for approximately 13% of somatic cells during embryogenesis (5)

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Findings from these studies have some applications to sedentary, postmenopausal women