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Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer

This may explain the propagation of neuropsychiatric disorders and atherosclerotic complications in PD patients

[1] Presentation by Jill Furman, Director, Office of Compliance, CDER, FDA at the FDLI Enforcement Conference, December 2023

Hepatology 41:13131321 Kleinert M, Clemmensen C, Hofmann SM, Moore MC, Renner S, Woods SC, Huypens P, Beckers J, de Angelis MH, Schrmann A, Bakhti M, Klingenspor M, Heiman M, Cherrington AD, Ristow M, Lickert H, Wolf E, Havel PJ, Mller TD, Tschp MH (2018) Animal models of obesity and diabetes mellitus

For researchers focused specifically on MASLD, mazdutide offers an excellent risk-benefit profile