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10.1126/science.aad4017 144 TongH.JiangZ.SongL.TanK.YinX.HeC.et al (2024)

Methods: The AF of 52 common SNPs (AF 0.01) previously reported to be associated with incident liver disease and cirrhosis/HCC were sourced from the Genome Aggregation Database (gnomAD v3.1.2) and Mount Sinais Biobank (BioMe)

90 In this process, epithelial cells lose their characteristic structure and functions, including cell polarity, tight junctions, and intercellular adhesion, and gain the morphology and functions of mesenchymal cells, including cell migration, invasion, and resistance to apoptosis