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The principal serious adverse reactions during this use are: (1) Ovarian hyperstimulation, a syndrome of sudden ovarian enlargement, ascites with or without pain, and/or pleural effusion

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A follow-up study using similar methods, which also included younger and older groups of males and females, found that regardless of the age group, males and females had similar AER per unit of liver volume (207)

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Castaldo G, Marino C, D'Elia M, et al