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Originally developed to combat obesity, researchers discovered that this specific fragment retains the fat-burning properties of hGH without affecting blood sugar levels or stimulating unwanted tissue growth

Lipophagy: connecting autophagy and lipid metabolism

NNMT is overexpressed in select tissues (e.g., adipose tissue, skeletal muscle, etc.) in pathophysiological conditions, making it a clinically relevant target for drug development in several chronic diseases including obesity and diabetes

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Protein enrichment analysis showed that DPI and MitoQ single treatments induced a similar profile of downregulated peptides, affecting mainly members of the complex I of the mitochondrial respiratory chain and cell cycle/division proteins ( Supplementary Figures S3 , S4