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Basics of Enzymes (used to monitor response to therapy) CK Aldolase Aldolase Becker Muscular Dystrophy AST AST Enzymes of the transferase class that catalyze the conversion of l-aspartate and 2-ketoglutarate to oxaloacetate and l-glutamate

Mechlovich D, Amit T, Bar-Am O, Weinreb O, Youdim MBH (2014) Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitus

Front Immunol 12:787307

The therapeutic effect of GDNF is time-dependent: early intervention during the reversible stage of neuronal degeneration yields significantly better outcomes than late intervention, highlighting its potential as a disease-modifying agent

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