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coli ET05, respectively

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Using the constructed evolutionary tree combined with the TimeTree database (www.timetrees.org) and the literature, we obtained time correction points

Future investigations utilizing targeted mechanistic interventions and causal experimental approaches (e.g., specific pathway inhibitors or genetic models) are warranted to clarify direct cause-and-effect relationships

There was a significant effect of voxel (ACC, SMA, OCC), a significant effect of group (OCD vs HV), and a trend for the group and voxel interaction