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Further assessment of EGFP-NINJ1 interactions with endogenous xCT or E-cadherin using specific antibodies revealed a strong merged signal between endogenous xCT and EGFP-NINJ1 (Supplemental Fig

10.1161/circresaha.117.311401 9 FuX.CateS

Histological validation Mice bearing 4T1 tumors were intravenously injected PBS, free ICG, ICG/L-TPP, ICG/L-G2R-SA, and ICG/L-G2R-DA (ICG, 7.5 mg/kg), respectively