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Similar content being viewed by others Introduction In the last decade, it has emerged that intestinal permeability may be a risk factor for cardiometabolic diseases, contributing to inflammatory sequalae and subsequent disease progression [1]

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Drug displaced from plasma protein will of course distribute throughout the volume of distribution, so that a 5% increase in the amount of unbound drug in the body produces at most a 5% increase in pharmacologically active unbound drug at the site of action