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Such encapsulation of metal ions in the protein interior might hinder their dissociation and exclude formation of ternary ligand exchange complexes leading to kinetical inertness of the CuCP complex at pH 7.4

Future studies are needed to clarify connections between these two diseases and determine if modulating the endogenous oxalate pathway could be a treatment option to prevent CaOx kidney stone formation in patients with MASLD

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However, by 24 months, the effect of abatacept treatment on symptom burden and subclinical inflammation as determined by ultrasound was not sustained

Tanda-tanda gangguan ginjal, termasuk perubahan signifikan pada frekuensi buang air kecil atau pembengkakan pada kaki dan pergelangan kaki