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1 Introduction The depressive disorder (DD) in children and adolescents is a significant public health concern, given its detrimental outcomes that can result in serious health and socio-economic consequences in adulthood

Glycine is an excellent supplement to promote athletic performance and strengthening, helps repair muscle and joint damage, and improves sleep/wake cycle

Psychiatry 17 (10), 10171025

doi: 10.3389/fcimb.2021.765942 328 SayasC

SS-31 (elamipretide) , a mitochondria-targeted peptide that stabilizes cardiolipin to support energy production, became the first FDA-approved mitochondrial therapeutic in 2025, though only for the rare Barth syndrome, with the brain rationale still mechanistic and no cognitive trials