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For acquisition, cleared samples were imaged in a sagittal orientation (left lateral side up) on a light-sheet microscope (Miltenyi Blaze) equipped with a sCMOS camera and LVMI-Fluor 4 objective lens equipped with a 6-mm working distance dipping cap

Proportion who lost weight ( 5%) was 69% ( GLP1/GIP medication ) versus 57% (lower dose) versus 29% (PC)

3 Abate M, Di Carlo L, Di Iorio A, Salini V

Clin Rev Allergy Immunol 32:2336

Another small clinical trial, comprising six patients with GBM who underwent multiple cycles of BBB disruption using MRgFUS to enhance the penetration of TMZ chemotherapy, also found that MRgFUS is safe and well-tolerated without any significant long-term complications at 1-year follow-up [119]