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Hu H, Shih R, Rothenberg S, Schwartz BS

5Amino1MQ is a small molecule peptide that targets nicotinamide Nmethyltransferase (NNMT), an enzyme linked to fat storage and metabolic slowdown

383 In contrast, anti-inflammatory macrophages (M2) rely more extensively on sustained mitochondrial energy production, which is predominantly fueled by the -oxidation of fatty acids

Application with Glutathione Peroxidase - 1 Gene - Encoded Adenovirus Vector

(A) RT-qPCR analysis of CYP1A1 mRNA expression in HepG2-C3 cells following incubation with 4 M actinomycin D for 1 h and incubation with 10 nM TCDD or 10, 50 or 100 M skatole for 8 h (n = 3)