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This further confirms that the enhancement of Nrf2 is a viable strategy for activating the GSH system

Excess mitochondrial ROS production, causes cellular oxidative stress, sustains mitochondrial dysfunction and ROS production and perpetuates inflammation (Chang et al., 2021)

Hin y ang l sn phm ni bt trn th trng vi cng ngh vin ngm di li, gip Glutathione c hp thu trc tip vo h tun hon c th qua cc mao mch di li, mang li hiu qu lm sng da v chng lo ha u vit

DECLARATIONS Authors contributions Developed the model, ran simulations and analyses, interpreted the findings, and contributed to the writing and editing of the manuscript: Cruikshank A, Reed MC, Nijhout HF Availability of data and materials Computer models and codes used in this paper can be obtained from the authors by request

Glutathione is a tripeptide (containing 3 amino acids: cysteine, glutamic acid, and glycine) naturally made in human cells that functions as a powerful antioxidant