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Their interpretation, however, is inherently integrative and iterative: each datasetgenomic variants, biochemical abnormalities, polygenic modulation, and microbiome-derived pathwaysrefines the others as new information becomes available, allowing the multidisciplinary team to recalibrate the emerging clinical model

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5 and 6 and Extended Data Fig

This collaborative approach ensures that the treatment plan is not only safe but also tailored to meet the individuals unique health objectives

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