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Discussion It is important to investigate the molecular features of spermatogenesis for understanding the differences and conservatism of testicular development across different species [1, 16, 28]

Apigenin attenuates functional and structural alterations via targeting NF-kB/Nrf2 signaling pathway in LPS-induced parkinsonism in experimental rats: Apigenin attenuates LPS-induced Parkinsonism in experimental rats

For gross pathology, the gross lesions were assessed over the signs of skin reaction on day 1 and day 7 post single administration using the procedure of ISO 10993-10: Biological evaluation of medical devices-Part 10, Tests for irritation and skin sensitization (Draize test) and OECD 404 guideline for testing of chemicals (acute dermal irritation and corrosion)

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Skin brightening effects may take longer, especially if not paired with vitamin C