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J Pharm Pharmacol [Internet]

Currently, the Rome IV Diagnostic Criteria, which provides symptom-based criteria is generally applied for diagnosis of IBS and other functional gastrointestinal disorders (Lacy et al., 2016)

Longer photostimulation times exhibited weaker HyPer7 responses, likely because of oxidative damage to the KR protein which prevented further photosensitization 27,32,33