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Overexpression of aSyn in HEK293 cells lead to intracellular inclusions following exposure to a NO donor and oxidizing agents or ONOO 111,117

Under oxidative stress conditions, ROS are reduced by GSH with concomitant formation of the GSSG [37]

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Iron status in patients with pyruvate kinase deficiency: neonatal hyperferritinaemia associated with a novel frameshift deletion in the PKLR gene (p.Arg518fs), and low hepcidin to ferritin ratios

46 LncExACT1 is able to bind miR-222, while exercise-induced downregulation of lncExACT1 releases more miR-222 which in turn contributes to exercise-induced physiological cardiac hypertrophy