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J Neurochem 109(5):14591468

2) The results of this study completed by McCoy et al systematically evaluated the metabolic stability, BBB permeability, procognitive activity, and synaptogenic potential of Dihexa and other Nle-AngIV analogs, ultimately aiming to identify a therapeutic agent for dementia

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In addition, it has been postulated that laminar damage is associated with oxygen deprivation and disruption of the retrograde axonal flow of neurotrophic factors leading to secondary death of RGCs (Quigley et al., 2000

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