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M.LondonoR.WolfM

The fact remains that dual agonism beats single agonism in clinical trials

doi:10.1007/s40263-013-0039-0

Elevating NAD + has been demonstrated to exert unintended consequences, including off-target effects on sirtuins, PARPs, and CD38, which may result in immune dysregulation or altered DNA repair responses (Covarrubias et al