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Animal experiments were approved by the Ethics Review Committee of the First Affiliated Hospital of Nanchang University and conducted according to the guidelines of the Care and Use of Laboratory Animals by the National Institute of Health, China

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As the main problem lies in the lack of endogenous insulin production, all T1DM subjects will have low portal insulin levels, even when treated with subcutaneous insulin, as this will only increase systemic insulin concentrations

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Combining ginger and curcumin can therefore lead to an increased risk of bleeding, particularly when co-administered with conventional antiplatelet or anticoagulant medications