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It exhibits potent effects against ferroptosis and modifies the composition and structure of the gut microbiota, offering protective benefits in diabetic cardiomyopathy mice (130)

Results revealed that muscle stem cell proliferation and fusion were substantially elevated in treated aged mice, supporting nearly twofold greater myofiber cross-sectional area and shifts in fiber size distribution toward larger, healthier muscle fibers

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Metformin is associated with higher relative abundance of mucin-degrading Akkermansia muciniphila and several short-chain fatty acid-producing microbiota in the gut