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317 Stimulating the human lung cancer cell line A549 with products isolated from cancer patient-enriched bacteria was shown to promote the overexpression of genes related to the phosphatidylinositol 3-kinase (PI3K) and extracellular signal-regulated kinase 1/2 signaling pathways

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As the infection progresses, helminths induce the proliferation of Tregs and immunoregulatory Mo along with high levels of immunosuppressive cytokines TGF- and IL-10 (71)

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Conversely, in WT mice, JNK pathway was activated from 2 to 40 h as evidenced by the enhanced phosphorylation levels of JNK, c-Jun and ATF2 (Figure 6)