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The findings may pave the way toward the development of 15LO1 inhibitors as asthma treatments

RNA-Seq data from 2 different cohorts (SARP and IMSA [GSE 158752]) were analyzed

Methods Enzymol 52:302310 Carlos-Reyes A, Muiz-Lino MA, Romero-Garcia S, Lpez-Camarillo C, Hernndez-de la Cruz ON (2021) Biological adaptations of tumor cells to radiation therapy

DNA repair pathways including nucleotide excision repair (Ko:03420) and homologous recombination (Ko:03440) ensured efficient DNA damage response, while ATP-dependent chromatin remodeling (Ko:05202) mediated epigenetic reprogramming