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Manufactured in the USA with global ingredients in a cGMP-certified facility for quality and purity

Krzywinski, M

Calabrese, V., Cornelius, C., Mancuso, C., Lentile, R., Stella, A

10.1002/ijc.23876 228

observed that a combined administration of low doses of tryptophan (500 mg), niacin (100 mg), calcium (500 mg calcium carbonate), caffeine (64 mg), and acetylsalicylic acid (ASA) (650 mg) shortly after migraine attack resulted in beneficial effects in 9 out of 12 migraine patients (42)