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All reported PROTACs demonstrated potent anti-proliferative effects against several diverse types of cancer cell lines (IC 50 values between 0.16 and 86.3 M), with a pronounced effect on the human pharyngeal squamous cell carcinoma FaDu cell line (IC 50 values between 0.16 M and 2.39 M)

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In order to stay protected, there are recommendations from medical experts to use a barrier method like condoms or might consider switching to a non-oral form of contraception such as IUD, implant, or injection

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Where AOD 9604 targets fat cells directly, tirzepatide works through the incretin system, a network of hormones that regulate appetite, digestion, and insulin secretion from the gut level upward