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The Dose: Stimulating but Never Satisfying The tobacco industry learned as early as the 1960s [PDF] that addiction doesn't happen by accident: it begins with precise dosing

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To our knowledge, this is the first study reporting on the barriers and facilitators in cessation attempts for tobacco users with concomitant mental illness attending group tobacco cessation therapy in Nairobi, Kenya

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When you consume nicotine, it enters your bloodstream and is metabolized into various compounds, including cotinine