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thus, cells shift from a neuroprotective to a neurodegenerative role towards motor neurons, and thus are potential therapeutic targets [78]

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Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits

These compounds bind to receptors and trigger defined responses within the body

Acetaminophen, which is metabolized primarily by sulfation and glucuronidation, can also be oxidized by CYPs to form N-acetyl-p-benzoquinone imine (NAPQI)